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Cofocain

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  • Name Cofocain
  • EINECSN/A
  • CAS No. 8013-38-5
  • Densityg/cm3
  • PSA117.38000
  • LogP2.12130
  • SolubilityN/A
  • Melting PointN/A
  • FormulaC13H20N2O2•C8H10N4O2•ClH
  • Boiling Point373.6°Cat760mmHg
  • Molecular Weight467.03
  • Flash Point179.8°C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyA poison by subcutaneous and intracerebral route. When heated to decomposition it emits toxic vapors of NOx and HCl.
  • Risk CodesN/A
  • Molecular Structure
    Molecular Structure of 8013-38-5 (Impletol)
  • Hazard SymbolsN/A
  • SynonymsN/A

Cofocain Chemical Properties

IUPAC Name: 2-Diethylaminoethyl 4-aminobenzoate; 1,3,7-trimethylpurine-2,6-dione; hydrochloride
Synonyms of Cofocain (CAS NO.8013-38-5) : Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione ; Cofocain ; Impletol
CAS NO:8013-38-5
Molecular Formula of Cofocain (CAS NO.8013-38-5) : C21H31ClN6O4
Molecular Weight of Cofocain (CAS NO.8013-38-5) :466.9616
Molecular Structure of Cofocain (CAS NO.8013-38-5) :
Flash Point: 179.8 °C
Enthalpy of Vaporization: 62.09 kJ/mol
Boiling Point: 373.6 °C at 760 mmHg
Vapour Pressure: 8.84E-06 mmHg at 25°C

Cofocain Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 270mg/kg (270mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 1, Pg. 28, 1951.
rabbit LD50 intracrebral 4100ug/kg (4.1mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 137, 1959.

Cofocain Safety Profile

A poison by subcutaneous and intracerebral route. When Cofocain (CAS NO.8013-38-5) is heated to decomposition it emits toxic vapors of NOx and HCl.

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