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ConjugatedEstrogens

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  • Name ConjugatedEstrogens
  • EINECS235-199-5
  • CAS No. 12126-59-9
  • DensityN/A
  • PSA91.88000
  • LogP3.95170
  • SolubilityN/A
  • Melting PointN/A
  • FormulaUnspecified
  • Boiling PointN/A
  • Molecular Weight370.39500
  • Flash PointN/A
  • Transport InformationN/A
  • AppearanceWhite needle crystal
  • Safety
  • Risk CodesN/A
  • Molecular Structure
    Molecular Structure of 12126-59-9 (Premarin)
  • Hazard SymbolsN/A
  • SynonymsN/A

ConjugatedEstrogens Specification

1. Introduction of ConjugatedEstrogens
ConjugatedEstrogens is a dark yellow to orange powder. ConjugatedEstrogens belongs to the product categories which is Steroids. Besides, the Classification Code of this chemical is Drug / Therapeutic Agent; Estrogens; Hormone; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Natural Product; Reproductive Effect; Tumor data.

2. Toxicity of ConjugatedEstrogens

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 1740mg/kg (1740mg/kg)   Drugs in Japan Vol. -, Pg. 178, 1990.
rat LD50 intraperitoneal 325mg/kg (325mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

3. Uses of ConjugatedEstrogens
ConjugatedEstrogens is the commercial name for a compound cream of vaginally administered estrogens, consisting primarily of conjugated estrogens. It is available in oral (0.3/ 0.45/ 0.625/ 0.9/ 1.25 mg), IV, and topical form. ConjugatedEstrogens can be used for menopause and postmenopausal estrogen replacement therapy and is the most commonly used drugs.

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