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ConjugatedEstrogens

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Name

ConjugatedEstrogens

EINECS 235-199-5
CAS No. 12126-59-9 Density N/A
PSA 91.88000 LogP 3.95170
Solubility N/A Melting Point N/A
Formula Unspecified Boiling Point N/A
Molecular Weight 370.39500 Flash Point N/A
Transport Information N/A Appearance White needle crystal
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 12126-59-9 (Premarin) Hazard Symbols N/A
Synonyms

Estrogens,conjugates;Ayerogen;Ayerogen Crema Vaginal;Azumon;C.E.S.;Cenestin;Climarest;Conjugated estrogens;Conjugates, estrogens;Conjugen;Dagynil;Emopremarin;Equin;Femavit;Hyphorin;Mannest;Menopak E;Menpoz;Neo-Menovar;Oestro-Feminal;Ovest;Premaril;Premarin Crema V;Premarin Creme;Premarin Vaginal Creme;Premarina;Premarose;Presomen;Prevagin-Premaril;Romeda;Sefac;Srogen;Sukingpo;Transannon;Testosterone Phenylpropionate;Estrogens, conjugated;

 

ConjugatedEstrogens Specification

1. Introduction of ConjugatedEstrogens
ConjugatedEstrogens is a dark yellow to orange powder. ConjugatedEstrogens belongs to the product categories which is Steroids. Besides, the Classification Code of this chemical is Drug / Therapeutic Agent; Estrogens; Hormone; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Natural Product; Reproductive Effect; Tumor data.

2. Toxicity of ConjugatedEstrogens

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 1740mg/kg (1740mg/kg)   Drugs in Japan Vol. -, Pg. 178, 1990.
rat LD50 intraperitoneal 325mg/kg (325mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

3. Uses of ConjugatedEstrogens
ConjugatedEstrogens is the commercial name for a compound cream of vaginally administered estrogens, consisting primarily of conjugated estrogens. It is available in oral (0.3/ 0.45/ 0.625/ 0.9/ 1.25 mg), IV, and topical form. ConjugatedEstrogens can be used for menopause and postmenopausal estrogen replacement therapy and is the most commonly used drugs.

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