The Cryptating agent 221 is an organic compound with the formula C₁₆H₃₂N₂O₅. The IUPAC name of this chemical is 4,7,13,16,21-pentaoxa-1,10-diazabicyclo[8.8.5]tricosane. With the CAS registry number 31364-42-8 and EINECS 250-592-1, it is also named as 2,2,1-Cryptand. The product's category is FDG Chemicals. It is liquid which shoud avoid oxidate. When using it, people should not breathe vapour and avoid contact with skin and eyes. Additionally, this chemical should be sealed in the container and stored in the cool and dry place. People should ensure that the workplace has well-ventilated equipment

The other characteristics of Cryptating agent 221 can be summarized as: (1)ACD/LogP: -1.20; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.82; (4)ACD/LogD (pH 7.4): -1.44; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 3.04; (9)#H bond acceptors: 7; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 52.63 Å²; (13)Index of Refraction: 1.505; (14)Molar Refractivity: 88.52 cm³; (15)Molar Volume: 298.4 cm³; (16)Surface Tension: 43.4 dyne/cm; (17)Enthalpy of Vaporization: 72.7 kJ/mol; (18)Vapour Pressure: 7.72E-09 mmHg at 25°C; (19)Exact Mass: 332.231122; (20)MonoIsotopic Mass: 332.231122; (21)Topological Polar Surface Area: 52.6; (22)Heavy Atom Count: 23; (23)Complexity: 237.

Preparation of Cryptating agent 221: It can be obtained by C₁₈H₃₈N₂O₅(2+)*2I(1-). This reaction needs reagent triphenylphosphine and solvent dimethylformamide by heating. The reaction time is 5 hours. The yield is 80%.

People can use the following data to convert to the molecule structure. 
1. SMILES:O2CCN1CCOCCOCCN(CCOCC1)CCOCC2
2. InChI:InChI=1/C16H32N2O5/c1-7-19-8-2-18-5-11-22-15-13-20-9-3-17(1)4-10-21-14-16-23-12-6-18/h1-16H2
3. InChIKey:HDLXPNDSLDLJHF-UHFFFAOYAK
4. Std. InChI:InChI=1S/C16H32N2O5/c1-7-19-8-2-18-5-11-22-15-13-20-9-3-17(1)4-10-21-14-16-23-12-6-18/h1-16H2 
5. Std. InChIKey:HDLXPNDSLDLJHF-UHFFFAOYSA-N