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DIHYDROCODEINE BITARTRATE

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Name

DIHYDROCODEINE BITARTRATE

EINECS 204-732-3
CAS No. 5965-13-9 Density 1.31 g/cm3
PSA 156.99000 LogP -0.45960
Solubility N/A Melting Point 192 °C (decomp)
Formula C18H23NO3•C4H6O6 Boiling Point 462 °C at 760 mmHg
Molecular Weight 451.474 Flash Point 233.2 °C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intraperitoneal, subcutaneous, and parenteral routes. Human systemic effects by intravenous route: irritability. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE. Risk Codes N/A
Molecular Structure Molecular Structure of 5965-13-9 (DIHYDROCODEINE BITARTRATE CII (200 MG)I0D2050.997MG/MG(DR)) Hazard Symbols N/A
Synonyms

Paracodeine bitartrate;dihydrocodeine tartrate;Dihydrocodeine acid tartrate;DF 118;Dihydrocodeine bitartrate;Dihydrocodein-hydrogentartrat;Dihydrocodeine Bitartrate [USP];Tuscodin;

 

DIHYDROCODEINE BITARTRATE Chemical Properties

Molecular Formula:C18H23NO3·C4H6O6
Molecular Weight:451.52
EINECS:204-732-3
Melting Point:186-190 °C (367 - 374F)
Density:1.31 g/cm3
Boiling Point:462 °C at 760 mmHg
Flash Point:233.2 °C
Solubility:22 mg/100 ml water.
Properties:Crystals from
Dihydrocodeine Bitartrate's(5965-13-9) Synonyms: 4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-alpha-otartrate(1:1);4,5alpha-epoxy-3-methoxy-17-methyl-morphinan-6alpha-otartrate(1:1)(sal;df118;dihydrocodeineacidtartrate;dihydrocodeinebitartrate;dihydro-codeintartrate(1:1);DIHYDROCODEINE BITARTRATE CII (200 MG)I0D2050.997MG/MG(DR);4,5alpha-epoxy-6alpha-hydroxy-3-methoxy-17-methylmorphinan hydrogen [R-(R*,R*)]-tartrate
Dihydrocodeine Bitartrate's(5965-13-9) Molecular Structure:

DIHYDROCODEINE BITARTRATE Toxicity Data With Reference

1.   

ivn-hmn TDLo:357 µg/kg/5M-C:CNS

   LANCAO    Lancet. 1 (1982),1425.
2.   

orl-rat LD50:240 mg/kg

   TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),42.
3.   

ipr-mus LD50:252 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 136 (1962),333.
4.   

scu-mus LDLo:350 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 51 (1934),35.
5.   

scu-rbt LDLo:39 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 66 (1939),182.
6.   

par-rbt LDLo:116 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 66 (1939),182.

DIHYDROCODEINE BITARTRATE Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and parenteral routes. Human systemic effects by intravenous route: irritability. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.

DIHYDROCODEINE BITARTRATE Specification

Stability and Reactivity of Dihydrocodeine Bitartrate(5965-13-9)
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.

Fire Fighting Measures for Dihydrocodeine Bitartrate(5965-13-9)
Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.