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DL-Noradrenaline

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Name

DL-Noradrenaline

EINECS 200-229-8
CAS No. 138-65-8 Density 1.397 g/cm3
PSA 86.71000 LogP 0.79020
Solubility N/A Melting Point ~190 °C (dec.)
Formula C8H11 N O3 Boiling Point 442.6 °C at 760 mmHg
Molecular Weight 169.18 Flash Point 221.5 °C
Transport Information N/A Appearance N/A
Safety Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx. Risk Codes 28-41
Molecular Structure Molecular Structure of 138-65-8 (DL-Noradrenaline) Hazard Symbols VeryT+
Synonyms

1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)-, (?à)-; Arterenol, dl- (5CI); Benzyl alcohol, a-(aminomethyl)-3,4-dihydroxy-, (?à)- (8CI); (?à)-Noradrenaline; (?à)-Norepinephrine;1-(3,4-Dihydroxy)phenyl-2-aminoethanol; 2-Amino-1-(3,4-dihydroxyphenyl)ethanol;4-(1-Hydroxy-2-aminoethyl)catechol; 4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol;DL-Arterenol; DL-Noradrenaline; DL-Norepinephrine; NSC 294898; Racemicnorepinephrine; dl-Noradrenaline; dl-Norepinephrine; a-(Aminomethyl)-3,4-dihydroxybenzylalcohol

Article Data 22

DL-Noradrenaline Chemical Properties

Molecular Structure of DL-Noradrenaline (CAS NO.138-65-8):


IUPAC: 4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol
EINECS:205-337-9
Molecular Formula:C8H11NO3
Molecular Weight:169.18
Storage temp.:2-8oC
Density:1.397g/cm3
Melting Point:~190oC (dec.)
Boiling Point:442.6oC at 760 mmHg
Flash Point:221.5oC
Index of Refraction:1.659 
Molar Volume:121cm
Molar Refractivity:44.63 cm3 
Vapour Pressure:1.3E-08 mmHg at 25o
Enthalpy of Vaporization:73.79kJ/mol
Surface Tension:76.7dyne/cm  
Merck:6695

DL-Noradrenaline Toxicity Data With Reference

1.    

ivn-rat LD50:130 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 95 (1949),502.
2.    

ivn-mus LD50:4700 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 95 (1949),502.

DL-Noradrenaline Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx.
Safty informations about DL-Noradrenaline (CAS NO.138-65-8):
Hazard Codes:T+Very
Risk Statements:28-41
R28:Very toxic if swallowed.
R41:Risk of serious damage to the eyes.
Safety Statements:28-36/37/39-45
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany:3
RTECS:DN6300000
F:8-10-23

DL-Noradrenaline Specification

 DL-Noradrenaline with cas registry number of 138-65-8 is also known as DL-norepinephrine ; DL-noradrenaline ; 1,2-Benzenediol,4-(2-amino-1-hydroxy)-,(dl)- ; 1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)- ; 1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)-,(.+/-.)- ; 4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol ; 4-Dihydroxy-alpha-(aminomethyl)-(+-)-benzylalcoho . It is a solid that can be soluble in water. It is used as a medicine to prevent shock, but it also may caused a rise of mean pulmonary artery pressure. In addition, it is a pharmaceutical Intermediate which is used to produce many useful medicines.

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