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Cas Database |
| Name |
Dithranol |
EINECS | 214-538-0 |
| CAS No. | 1143-38-0 | Density | 1.419 g/cm3 |
| PSA | 57.53000 | LogP | 2.23300 |
| Solubility | <0.1 g/100 mL at 20 °C in water | Melting Point |
178-181 °C(lit.) |
| Formula | C14H10O3 | Boiling Point | 464.1 °C at 760 mmHg |
| Molecular Weight | 226.232 | Flash Point | 248.6 °C |
| Transport Information | N/A | Appearance | yellow crystalline solid |
| Safety | 26-53-45 | Risk Codes | 36/37/38-45 |
| Molecular Structure |
|
Hazard Symbols |
 Xi, T
|
| Synonyms |
Anthrone,1,8-dihydroxy- (6CI,7CI,8CI);1,8-Dihydroxy-9-anthrone;1,8-Dihydroxyanthrone;Anthra-Derm;Batidrol;Batridol;Chrysodermol;Cignolin;Cigthranol;Derobin;Dithranol;DrithoCreme;Drithoscalp;Lasan;NSC 43970;NSC 629313;Psodadrate;Psoriacid-Stift;Psoriacide; |
Article Data | 29 |
Dithranol Chemical Properties
Chemical Name: Anthralin
IUPAC NAME: 1,8-Dihydroxy-10H-anthracen-9-one
CAS No.: 1143-38-0
EINECS: 214-538-0
RTECS: CB8927000
Molecular Formula: C14H10O3
Molecular Weight: 226.23 g/mol
Melting Point: 178-181 °C(lit.)
Density: 1.419 g/cm3
Flash Point: 248.6 °C
Boiling Point: 464.1 °C at 760 mmHg
Following is the structure of Dithranol (1143-38-0):
Product Categories about Dithranol (1143-38-0) are Aromatic Phenols ; Intermediates & Fine Chemicals ; Pharmaceuticals
The chemical synonymous of Dithranol (1143-38-0) are Dithranol ; Dithranol, anthralin ; Anthralin ; 1,8-Dihydroxy-10h-anthracen-9-one ; 1,8-Dihydroxy-9(10h)-anthracenone ; 1,8-Dihydroxyanthrone ; 1,8,9-Anthracenetriol ; 1,8-Dihydroxy-9(10h)-anthracenon
Dithranol Uses
The major use of Dithranol is as an treatment for psoriasis,it also used as a dermatology medication.
Dithranol Toxicity Data With Reference
| 1. | skn-hmn 0.1%/20M MLD | ADVEA4 Acta Dermato-Venereologica. 67 (1987),72. | ||
| 2. | skn-hmn 0.05%/12H | ADVEA4 Acta Dermato-Venereologica. 18 (1988),117. | ||
| 3. | skn-hmn 0.1%/1H MLD | ADVEA4 Acta Dermato-Venereologica. 67 (1987),72. | ||
| 4. | skn-hmn 0.0025%/24H MLD | ADVEA4 Acta Dermato-Venereologica. 63 (1983),513. | ||
| 5. | skn-hmn 0.01%/24H open | ADVEA4 Acta Dermato-Venereologica. 173 (1986),288. | ||
| 6. | skn-hmn 0.02%/48H MOD | ADVEA4 Acta Dermato-Venereologica. 93 (1989),695. |
Dithranol Safety Profile
A mild skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:
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T: Toxic .gif){kind=small}
Risk Statements about Dithranol (1143-38-0):
R45 May cause cancer.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Dithranol (1143-38-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 Avoid exposure - obtain special instructions before use.
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