Basic Information | Post buying leads | Suppliers |
Name |
Dominal |
EINECS | N/A |
CAS No. | 303-69-5 | Density | 1.168g/cm3 |
PSA | 44.67000 | LogP | 3.70100 |
Solubility | N/A | Melting Point |
25°C |
Formula | C16H19 N3 S | Boiling Point | 430.8°Cat760mmHg |
Molecular Weight | 285.44 | Flash Point | 214.3°C |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
10H-Pyrido[3,2-b][1,4]benzothiazine,10-[3-(dimethylamino)propyl]- (6CI,8CI); 10-(3-Dimethylaminopropyl)-10H-pyrido[3,2-b][1,4]benzothiazine;2,3-Pyridino-(5',6')-5,6-benzo-4-(3''-dimethylaminopropyl)-1,4-thiazine;Dominal; LG 206; Largophren; MH 05101; Phrenotropin; Prothipendyl; Timoval;Timovan; Tumovan |
Molecule structure of Dominal (CAS NO.303-69-5) :
IUPAC Name: N,N-dimethyl-3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-1-amine
Molecular Weight: 285.40716 g/mol
Molecular Formula: C16H19N3S
Density: 1.168 g/cm3
Melting Point: < 25 °C
Boiling Point: 430.8 °C at 760 mmHg
Flash Point: 214.3 °C
Index of Refraction: 1.621
Molar Refractivity: 85.95 cm3
Molar Volume: 244.1 cm3
Polarizability: 34.07*10-24 cm3
Surface Tension: 48.7 dyne/cm
Enthalpy of Vaporization: 68.63 kJ/mol
Vapour Pressure: 1.26E-07 mmHg at 25 °C
log P (octanol-water): 4.010
Atmospheric OH Rate Constant: 1.98E-10 cm3/molecule-sec
XLogP3-AA: 3.4
H-Bond Acceptor: 3
Rotatable Bond Count: 4
Exact Mass: 285.129968
MonoIsotopic Mass: 285.129968
Topological Polar Surface Area: 19.4
Heavy Atom Count: 20
Complexity: 310
Canonical SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1N=CC=C3
InChI: InChI=1S/C16H19N3S/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19/h3-5,7-10H,6,11-12H2,1-2H3
InChIKey Dominal (CAS NO.303-69-5) : JTTAUPUMOLRVRA-UHFFFAOYSA-N
1. | ivn-rat LD50:25 mg/kg | THERAP Therapie. 18 (1963),373. | ||
2. | orl-mus LD50:415 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489. | ||
3. | ipr-mus LD50:155 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),489. | ||
4. | scu-mus LD50:102 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),374. |
Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Dominal (CAS NO.303-69-5) is also called 10-(3-Dimethylaminopropyl)-1-azaphenothiazin ; 10-(3-Dimethylaminopropyl)-10H-pyrido(3,2-b)(1,4)benzothiazin ; 10H-Pyrido(3,2-b)(1,4)benzothiazine-10-propanamine, N,N-dimethyl- ; 4-27-00-07169 (Beilstein Handbook Reference) ; AY 56031 ; BRN 0259865 ; D 206 ; Dimethylamino-n-propyl-thiophenylpyridylamine ; Largophren ; MH 05101 ; Prothipendyl ; Prothipendylum [INN-Latin] ; Protipendilo [INN-Spanish] ; Timoval ; Timovan ; Tolnate ; Tumovan ; UNII-5O6VWA87VA .