Droperidol  is discovered at Janssen Pharmaceutica in 1961, droperidol is a butyrophenone, and is a potent D₂ (dopamine receptor) antagonist with some histamine and serotonin antagonist activity.
It has a central antiemetic prevents postoperative nausea and vomiting in adults using doses as low as 0.625 mg,and as an intramuscular injection,an antipsychotic in doses ranging from 5 to 10 mg given. When use in intramuscular sedation has been replaced by intramuscular preparations of haloperidol, midazolam, clonazepam and olanzapine.

The Droperidol, with the CAS registry number 548-73-2 and EINECS registry number 208-957-8, has the systematic name of 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one. It is a kind of pale yellow solid, and belongs to the following product categories: Heterocyclic Compounds; Intermediates & Fine Chemicals; Pharmaceuticals. The molecular formula of this chemical is C₂₂H₂₂FN₃O₂. It is harmful if swallowed. Therefore, you had better wear suitable protective clothing while dealing with this chemical. What's more, it should be stored at 2-8 °C.

The physical properties of Droperidol are as following: (1)ACD/LogP: 3.51; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.46; (4)ACD/LogD (pH 7.4): 3.11; (5)ACD/BCF (pH 5.5): 2.44; (6)ACD/BCF (pH 7.4): 108.17; (7)ACD/KOC (pH 5.5): 17.22; (8)ACD/KOC (pH 7.4): 763.15; (9)#H bond acceptors: 5; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 43.86 Å²; (13)Index of Refraction: 1.613; (14)Molar Refractivity: 104.06 cm³; (15)Molar Volume: 298.7 cm³; (16)Polarizability: 41.25×10^-24cm³; (17)Surface Tension: 51.3 dyne/cm; (18)Density: 1.269 g/cm³.

Preparation of Droperidol: It can be synthesized from 1-benzyl-3-carbethoxypiperidin-4-one, which is reacted with o-phenylendiamine. Under the reaction conditions, 1,5-benzdiazepine rearranges into 1-(1-benzyl-1,2,3,6-tetrahydro-4-piridyl)-2-benzymidazolone. Debenzylation of the resulting product with hydrogen over catalyst palladium, and subsequent alkylation of this using 4-chloro-4'-fluorobutyrophenone, and the yield is droperidol.

Uses of Droperidol: It is a D1, D2 dopamine receptor antagonist and used as butyrophenone antipsychotic and anti-emetic. It is also used for the treatment of neuroleptanalgesic anesthesia and sedation in intensive-care.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1ccc(cc1)C(=O)CCCN4C/C=C(/N3c2ccccc2NC3=O)CC4
(2)InChI: InChI=1/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
(3)InChIKey: RMEDXOLNCUSCGS-UHFFFAOYAS

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TDLo	oral	223ug/kg/12D- (0.223mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 93, 1972.
man	TDLo	intravenous	133ug/kg (0.133mg/kg)	BEHAVIORAL: COMA	Journal of Clinical Psychiatry. Vol. 47, Pg. 94, 1986.
mouse	LD	oral	> 160mg/kg (160mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 205, 1963.
mouse	LD50	intraperitoneal	72mg/kg (72mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Zhonghua Mazuixue Zazhi. Chinese Journal of Anesthesiology. Vol. 5(2), Pg. 65, 1985.
mouse	LD50	intravenous	20mg/kg (20mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 205, 1963.
mouse	LD50	subcutaneous	125mg/kg (125mg/kg)		Toxicology and Applied Pharmacology. Vol. 6, Pg. 63, 1964.
rat	LD50	intravenous	30mg/kg (30mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 205, 1963.
rat	LD50	oral	750mg/kg (750mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	subcutaneous	> 100mg/kg (100mg/kg)		Drugs in Japan Vol. 6, Pg. 533, 1982.