1. Introduction of Drospirenone

Drospirenone, with the IUPAC Name of (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-hexadecahydro-10,13-dimethylspiro-[17H-dicyclopropa-6,7:15,16]cyclopenta[a]phenanthrene-17,2'(5H)-furan]-3,5'(2H)-dione), is one kind of off-white crystalline powder. This chemical belongs to the Product Categories which include Intermediates & Fine Chemicals; Pharmaceuticals; Steroids, and it has the Classification Code which include Aldosterone antagonist; Aldosterone antagonists; Hormone; Hormone Antagonists; Hormones, Hormone Substitutes, and Hormone Antagonists; Reproductive Effect.

2. Properties of Drospirenone

Drospirenone has the following datas: (1)Index of Refraction: 1.61; (2)Molar Refractivity: 100.4 cm³; (3)Molar Volume: 289.4 cm³; (4)Polarizability: 39.8×10-24 cm³; (5)Surface Tension: 51.2 dyne/cm; (6)Density: 1.26 g/cm³; (7)Flash Point: 241.6 °C; (8)Enthalpy of Vaporization: 83.27 kJ/mol; (9)Boiling Point: 552.2 °C at 760 mmHg; (10)Melting Point: 196-200 °C ; (11)alpha: -180 °(c=0.5, chloroform) ; (12)Vapour Pressure: 3.07E-12 mmHg at 25 °C.

3. Structure Descriptors of Drospirenone

You could convert the following datas into the molecular structure:
(1). SMILES: O1C(CC[C@]21[C@@H]1[C@@H]([C@H]3[C@@H]4[C@@H]5[C@@H](C5)C5=CC(=O)CC[C@@]5([C@H]4CC[C@@]23C)C)C1)=O
(2). InChI: InChI=1/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1

4. Use of Drospirenone

Drospirenone is used as synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity.