1. Introduction of Eltrombopag

Eltrombopag, with the systematic name of 3-[3-[(N'E)-N'-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-pyrazol-4-ylidene]hydrazino]-2-hydroxy-phenyl]benzoic acid, is one kind of white crystalline powder, odorless, little bitter taste. It should be stored in dry and cool environment.

2. Properties of Eltrombopag

The properties of the chemical are: (1)ACD/LogP: 4.06; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.59; (4)ACD/LogD (pH 7.4): 0.75; (5)#H bond acceptors: 8; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 6; (8)Polar Surface Area: 114.59 Å²; (9)Index of Refraction: 1.666; (10)Molar Refractivity: 123.53 cm³; (11)Molar Volume: 332 cm³; (12)Polarizability: 48.97×10^-24cm³; (13)Surface Tension: 52.5 dyne/cm; (14)Enthalpy of Vaporization: 101.61 kJ/mol; (15)Vapour Pressure: 3.79×10^-18 mmHg at 25°C._.

3. Structure Descriptors of Eltrombopag

You can still convert the following datas into molecular structure:
(1)SMILES: OC(=O)c1cccc(c1)c4cccc(N\N=C3C(\C)=N/N(c2ccc(C)c(C)c2)C3=O)c4O
(2)InChI: InChI=1/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22+
(3)InChIKey: XDXWLKQMMKQXPV-HPNDGRJYBX