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Cas Database |
| Name |
Estradiol dipropionate |
EINECS | 204-026-5 |
| CAS No. | 113-38-2 | Density | 1.14g/cm3 |
| PSA | 52.60000 | LogP | 5.17990 |
| Solubility | N/A | Melting Point |
104-106℃ (ethanol ) |
| Formula | C24H32O4 | Boiling Point | 487.8°Cat760mmHg |
| Molecular Weight | 384.516 | Flash Point | 238.5°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | 22-24/25 | Risk Codes | 40-48 |
| Molecular Structure |
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Hazard Symbols |
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| Synonyms |
Estra-1,3,5(10)-triene-3,17-diol(17b)-, dipropanoate (9CI);Estradiol, dipropionate (6CI,7CI,8CI);1,3,5(10)-Estratriene-3,17b-diol dipropionate;17b-Estradiol 3,17-dipropionate;17b-Estradiol dipropionate;3,17b-Dipropionoxyestra-1,3,5(10)-triene;3,17b-Estradiol dipropionate;Agofollin;Dimenformon dipropionate;Diovocyclin;Diovocylin;Diprostron;EndofollicolinaD. P.;Estradiol 3,17-dipropionate;Estradiol propionate;Estroici;Estronex;Follicyclin P;Nacyclyl;Oestradiol 3,17-dipropionate;Ovahormon Depot;Ovocyclin P;Ovocyclin dipropionate;Progynon DP;b-Estradiol dipropionate; |
Article Data | 9 |
Estradiol dipropionate Consensus Reports
IARC Cancer Review: Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 21 , 1979,p. 279.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
Estradiol dipropionate Specification
Estradiol dipropionate , with cas register number of 113-38-2, is called EDP for short. Its IUPAC name is [(8R,9S,13S,14S,17S)-13-methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] propanoate and the systematic name is (17beta)-estra-1,3,5(10)-triene-3,17-diyl dipropanoate with the SMILES of O=C(Oc1cc3c(cc1)[C@H]2CC[C@@]4([C@@H](OC(=O)CC)CC[C@H]4[C@@H]2CC3)C)CC. Moreover, its superlist Name is called Oestradiol dipropionate . This compound is a kind of Steroids.
The physical properties of Estradiol dipropionate include: (1)H bond acceptors: 4; (2)H bond donors: 0; (3)Freely Rotating Bonds: 6; (4)Index of Refraction: 1.554; (5)Molar Refractivity: 107.59 cm3; (6)Molar Volume: 335.7 cm3 ; (7)Surface Tension: 45.5 dyne/cm; (8)Enthalpy of Vaporization: 75.38 kJ/mol; (9)Vapour Pressure: 1.15E-09 mmHg at 25°C.
Estradiol dipropionate is a poison by intravenous and parenteral routes. When heated to decomposition it emits acrid smoke and irritating fumes. It has the limited evidence of a carcinogenic effect and the danger of serious damage to health by prolonged exposure. When use it, do not breathe dust and avoid contact with skin and eyes.
Estradiol dipropionate is a drug for the treatment of menopause. It has the experimental reproductive effects. The toxicity has done like:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD | subcutaneous | > 10gm/kg (10000mg/kg) | Drugs in Japan Vol. -, Pg. 175, 1990. |
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