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Name	Ethyl (triphenylphosphoranylidene)acetate	EINECS	214-151-7
CAS No.	1099-45-2	Density	1.15 g/cm³
PSA	36.11000	LogP	3.34580
Solubility	Insoluble in water	Melting Point	125-127ºC
Formula	C₂₂H₂₁O₂P	Boiling Point	490.4 ºC at 760 mmHg
Molecular Weight	348.381	Flash Point	263.5 ºC
Transport Information	N/A	Appearance	white or slight yellow powder
Safety	22-24/25	Risk Codes	36/37/38-25-20/21/22
Molecular Structure		Hazard Symbols	T
Synonyms	(2-Ethoxy-2-oxoethylidene)triphenylphosphorane;(Carbethoxymethylene)triphenylphosphorane;(Carbethoxymethylidene)triphenylphosphorane;(Ethoxycarbonylmethylidene)triphenylphosphorane;(Triphenylcarbethoxymethylene)phosphorane;(Triphenylphosphanylidene)aceticacid ethyl ester;(Triphenylphosphoranylidene)acetic acid ethyl ester;Carbethoxytriphenylphosphonium methylide;NSC 72406;[(Ethoxycarbonyl)methylene]triphenylphosphorane;	Article Data	134

Ethyl (triphenylphosphoranylidene)acetate Chemical Properties

Molecular formula: C₂₂H₂₁O₂P
Molar mass: 348.37
Molecular Structure of Ethyl (triphenylphosphoranylidene)acetate(1099-45-2):

Synonyms of Ethyl (triphenylphosphoranylidene)acetate(1099-45-2):(ETHOXYCARBONYLMETHYLENE)TRIPHENYLPHOSPHORANE;(triphenylphosphoranylidene)-aceticaciethylester;ETHYL (TRIPHENYLPHOSPHORANYLIDEN)ACETATE;ETHYL (TRIPHENYLPHOSPHORANYLIDENE)ACETATE(CARBOETHOXYMETHYLENE)TRIPHENYLPHOSPHORANE;(CARBETHOXYMETHYLENE)TRIPHENYLPHOSPHORANE;ETHYL (TRIPHENYLPHOSPHORYLIDENE)ACETATE.
Melting point:128-131 °C
Hazard Note: Keep Cold
Sensitive: Air Sensitive
Water Solubility: Insoluble
storage temp: 2-8°C

Ethyl (triphenylphosphoranylidene)acetate Uses

Ethyl (triphenylphosphoranylidene)acetate(1099-45-2) is used in process of pharmaceutical synthesis as a common Wittig reagent and a cholinesterase inhibitor.
cholinesterase inhibitor could combines with the cholinesterase (ChE) and inhibits it's activity

Ethyl (triphenylphosphoranylidene)acetate Toxicity Data With Reference

Carcinogenicity of Ethyl (triphenylphosphoranylidene)acetate(1099-45-2): (Carbethoxymethylene)triphenylphosphorane - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.

Ethyl (triphenylphosphoranylidene)acetate Safety Profile

Hazard Codes T

,Xi

,Xn

Risk Statements:
20: Harmful by inhalation
21: Harmful in contact with skin
22: Harmful if swallowed
25: Toxic if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements :
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Ethyl (triphenylphosphoranylidene)acetate Specification

Hazardous Decomposition Products: Phosphine, carbon monoxide, oxides of phosphorus, carbon dioxide.
Chemical Stability: Stable under normal temperatures and pressures. Air sensitive. Moisture sensitive.
Incompatibilities with Other Materials: Strong oxidizing agents.
Conditions to Avoid: Incompatible materials, exposure to air, exposure to moist air or water.

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