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Name	Ethylmorphine	EINECS	200-970-7
CAS No.	76-58-4	Density	1.31 g/cm³
PSA	41.93000	LogP	1.82910
Solubility	2.794g/L(20 oC)	Melting Point	40-42°C
Formula	C19H23 N O3	Boiling Point	472.2 ºC at 760 mmHg
Molecular Weight	313.397	Flash Point	239.4 ºC
Transport Information	N/A	Appearance	N/A
Safety	Poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x. See also (−)-MORPHINE.	Risk Codes	22
Molecular Structure		Hazard Symbols	Xn
Synonyms	Morphinan-6a-ol, 7,8-didehydro-4,5a-epoxy-3-ethoxy-17-methyl- (8CI);Morphine, 3-O-ethyl- (7CI); 3-Ethoxymorphine; 3-O-Ethylmorphine; Codethyline;Diohin; Ethylmorphine; Morphine, ethyl-	Article Data	12

Ethylmorphine Chemical Properties

Empirical Formula: C₁₉H₂₃NO₃
Molecular Weight: 313.3908
EINECS: 200-970-7
Index of Refraction: 1.653
Density: 1.31 g/cm³
Flash Point: 239.4 °C
Enthalpy of Vaporization: 77.44 kJ/mol
Boiling Point: 472.2 °C at 760 mmHg
Vapour Pressure: 1.01E-09 mmHg at 25 °C
storage temp.: 2-8 °C
Structure of Ethylmorphine (CAS NO.76-58-4):

Ethylmorphine Uses

Ethylmorphine (CAS NO.76-58-4) has been invented in Germany at Merck in 1884 and was used as a weaker alternative to heroin for all indications. It is used as an antitussive to treat dry cough and also as a moderately strong analgesic. It is most widely used in ophthalmology for removing inflammation products from the eyes.

Ethylmorphine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	120mg/kg (120mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Annales Pharmaceutiques Francaises. Vol. 8, Pg. 261, 1950.
mouse	LD50	oral	520mg/kg (520mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 719, 1971.
mouse	LD50	subcutaneous	136mg/kg (136mg/kg)		"Public Health Reports, Supplement." Vol. 138, Pg. 8, 1938.
rat	LD50	intraperitoneal	110mg/kg (110mg/kg)		Pharmazie. Vol. 31, Pg. 655, 1976.
rat	LD50	intravenous	62mg/kg (62mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.
rat	LD50	oral	810mg/kg (810mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.
rat	LD50	subcutaneous	200mg/kg (200mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.

Ethylmorphine Safety Profile

Poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x. See also (−)-MORPHINE.

Hazard Codes: Harmful Xn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 36/37/39-45
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Ethylmorphine Specification

Ethylmorphine ,its cas register number is 76-58-4. It also can be called Ethomorphine ; Codethyline ; Dionine, and Ethyl morphine . It has a hydromorphone analogue, and a dihydromorphine analogue known as ethyldihydromorphine, and is potentially habit-forming and can generate drug dependence of the codeine type. Ethylmorphine (CAS NO.76-58-4) is 'less potent than morphine' but 'more potent than codeine' by a small percentage.Taking it in combination with alcohol or other drugs that have a suppressive effect on the central nervous system boosts both drugs' effects, creating a dangerous combination. It is converted to morphine in the human liver by the CYP450-isozyme CYP2D6, similarly to codeine. In most countries and internationally ethylmorphine and codeine are regulated much the same way.