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Etonogestrel

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Name

Etonogestrel

EINECS 258-936-2
CAS No. 54048-10-1 Density 1.13 g/cm3
PSA 37.30000 LogP 4.04870
Solubility N/A Melting Point 182-184 °C
Formula C22H28O2 Boiling Point 473.1 °C at 760 mmHg
Molecular Weight 324.463 Flash Point 201.1 °C
Transport Information N/A Appearance White Solid
Safety Risk Codes 60-40
Molecular Structure Molecular Structure of 54048-10-1 (Etonogestrel) Hazard Symbols N/A
Synonyms

17-Ethynyl-17b-hydroxy-18-methyl-11-methyleneestr-4-en-3-one;3-Keto-Org 2969;3-Ketodesogestrel;3-Oxodesogestrel;3-keto-Desogestrel;Implanon;Org 3236;18,19-Dinorpregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy-11-methylene-, (17a)-;

Article Data 8

Etonogestrel Chemical Properties


IUPAC Name: (8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
Empirical Formula: C22H28O2
Molecular Weight: 324.4565
EINECS: 258-936-2
Product Categories: Various Metabolites and Impurities; Intermediates & Fine Chemicals; Metabolites & Impurities; Pharmaceuticals; Steroids 
Index of Refraction: 1.574
Molar Refractivity: 94.35 cm3
Molar Volume: 285.6 cm3
Surface Tension: 47.1 dyne/cm
Density: 1.13 g/cm3
Flash Point: 201.1 °C
Enthalpy of Vaporization: 84.87 kJ/mol
Boiling Point: 473.1 °C at 760 mmHg
Vapour Pressure: 6.13E-11 mmHg at 25 °C 
Appearance: White Solid
Melting Point: 182-184 °C
Classification Code of Etonogestrel (CAS NO.54048-10-1): Contraceptive Agents; Contraceptive Agents, Female; Hormone; Human Data; Progestin; Reproductive Control Agents; Reproductive Effect

Etonogestrel Uses

 Etonogestrel is a molecule used in hormonal contraceptives, most notably the subdermal implant Implanon and the contraceptive vaginal ring NuvaRing. Etonogestrel, the specific progestin used in NuvaRing, is the active metabolite of the inactive prodrug desogestrel, one of two third-generation progestins found in some epidemiological studies of combined oral contraceptive pills to be associated with a higher risk of venous thrombosis than combined oral contraceptive pills containing certain second-generation progestins.

Etonogestrel Specification

  Etonogestrel (CAS NO.54048-10-1), its Synonyms are (17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one ; 13-Ethyl-11-methylene-18,19-dinor-17-alpha-pregn-4-en-20-yn-3-one ; 13-Ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one ; 17-Ethinyl-17-beta-hydroxy-18-methyl-11-methylene-4-estren-3-one ; 3-Keto-desogestrel ; 3-Ketodesogestrel ; 3-Oxodesogestrel ; Implanon .

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