- 436799-32-52-Trifluoromethyl-5-bromopyridine
- 436799-33-6Pyridine,3-bromo-5-(trifluoromethyl)-
- 436799-36-95-Bromo-2-(trifluoromethyl)-3-pyridinecarboxylic acid
- 4368-06-3Butanenitrile,3-hydroxy-
- 436810-99-0Bicyclo[2.2.1]hept-5-ene-2-carboxylicacid, 3-[(4-methyl-1-piperidinyl)carbonyl]-
- 436811-21-12-[(4R)-2-(benzothiazol-2-ylamino)-5-oxo-1,4-dihydroimidazol-4-yl]acetate
- 436811-33-5Imidazo[1,2-a]pyridine-3-aceticacid, 2,3-dihydro-3-methyl-2-oxo-
- 4368-28-95,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-,(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-
- 4368-51-81-Heptanaminium,N,N,N-triheptyl-, bromide (1:1)
- 4368-56-3C.I. Acid Blue 62
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Fangchinoline |
EINECS | N/A |
| CAS No. | 436-77-1 | Density | 1.204 g/cm3 |
| PSA | 72.86000 | LogP | 6.73520 |
| Solubility | N/A | Melting Point |
240～242℃ |
| Formula | C37H40N2O6 | Boiling Point | 709.7 °C at 760 mmHg |
| Molecular Weight | 608.734 | Flash Point | 383 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Berbaman-7-ol,6,6',12-trimethoxy-2,2'-dimethyl-, (1b)-;Fangchinoline (6CI,7CI,8CI);(+)-Fangchinoline;(+)-Limacine;16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol,3,4,4a,5,16a,17,18,19-octahydro-12,21,26-trimethoxy-4,17-dimethyl-,[4aS-(4aR*,16aR*)]-;7-O-Demethyltetrandrine;Frangchinoline;NSC 77036;Fangchinoline;(1-beta)-2,2'-Dimethyl-6,6',12-trimethoxyberbaman-7-ol; |
Article Data | 4 |
Fangchinoline Specification
The systematic name of Fangchinoline is (1β)-6,6',12-trimethoxy-2,2'-dimethylberbaman-7-ol. With the CAS registry number 436-77-1, it is also named as 7-O-Demethyltetrandrine. The product's categories are Alkaloids; Reference Substance. In addition, its molecular formula is C37H40N2O6 and molecular weight is 608.72.
The other characteristics of Fangchinoline can be summarized as: (1)ACD/LogP: 3.78; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 0.03; (4)ACD/LogD (pH 7.4): 3.01; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 75.27; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 465.68; (9)#H bond acceptors: 8; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 61.86 Å2; (13)Index of Refraction: 1.601; (14)Molar Refractivity: 173.32 cm3; (15)Molar Volume: 505.5 cm3; (16)Polarizability: 68.71×10-24cm3; (17)Surface Tension: 44.6 dyne/cm; (18)Density: 1.204 g/cm3; (19)Flash Point: 383 °C; (20)Enthalpy of Vaporization: 107.49 kJ/mol; (21)Boiling Point: 709.7 °C at 760 mmHg; (22)Vapour Pressure: 8.25E-21 mmHg at 25 °C.
People can use the following data to convert to the molecule structure.
(1)SMILES: Oc7c(OC)cc4c5c7Oc1cc2c(cc1OC)CCN(C)[C@H]2Cc6ccc(Oc3cc(ccc3OC)C[C@@H]5N(C)CC4)cc6
(2)InChI: InChI=1/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1
(3)InChIKey: IIQSJHUEZBTSAT-VMPREFPWBD
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | > 50mg/kg (50mg/kg) | Chemical and Pharmaceutical Bulletin. Vol. 24, Pg. 2413, 1976. |
What can I do for you?
Get Best Price
