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Feldene

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Name

Feldene

EINECS N/A
CAS No. 4551-59-1 Density 1.04g/cm3
PSA 62.13000 LogP 3.19580
Solubility N/A Melting Point 199°C
Formula C19H30 N2 O3 Boiling Point 488.3°Cat760mmHg
Molecular Weight 334.459 Flash Point 249.1°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS. Risk Codes N/A
Molecular Structure Molecular Structure of 4551-59-1 (fenalamide) Hazard Symbols N/A
Synonyms

Malonamicacid, N-[2-(diethylamino)ethyl]-2-ethyl-2-phenyl-, ethyl ester (6CI,7CI,8CI);Ethyl N-(2-diethylaminoethyl)-2-phenyl-2-ethylmalononamate; EthylN-[2-(N',N'-dimethylamino)-ethyl]-2-ethyl-2-phenylmalonamate; EthylN-[2-(diethylamino)ethyl]-2-ethyl-2-phenylmalonamate; Femamide; Fenalamide;Phemamide; SH 30858; Sch 5706; Spasmamide

Article Data 1

Feldene Chemical Properties


IUPAC Name: Ethyl 2-(2-diethylaminoethylcarbamoyl)-2-phenylbutanoate
Molecular Formula:C19H30N2O3                  
Molecular Weight :334.4531                                         
EINECS:224-917-2
Classification Code: Drug / Therapeutic Agent; Relaxant (smooth muscle)  
Index of Refraction: 1.505
Molar Refractivity: 95.45 cm3
Molar Volume: 321.3 cm3 
Surface Tension:  37.8 dyne/cm 
Density:  1.04 g/cm3 
Flash Point:  249.1 °C 
Enthalpy of Vaporization:  75.44 kJ/mol 
Boiling Point:  488.3 °C at 760 mmHg 
Vapour Pressure of  Feldene (CAS NO.4551-59-1):  1.1E-09 mmHg at 25 °C 

Feldene Toxicity Data With Reference

  Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 210mg/kg (210mg/kg)   Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972.
mouse LD50 oral 400mg/kg (400mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.
rat LD50 oral 610mg/kg (610mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.

Feldene Safety Profile

A human poison by ingestion. Poison experimentally by ingestion, subcutaneous, intraperitoneal, and rectal routes. Human systemic effects by ingestion: interstitial nephritis, metabolic acidosis, dermatitis, agranulocytosis. An experimental teratogen. Other experimental reproductive effects. When Feldene (CAS NO.4551-59-1) is heated to decomposition, it emits toxic fumes of SOx and NOx.

Feldene Specification

  Feldene (CAS NO.4551-59-1), its Synonyms areBenzeneacetic acid, alpha-(((2-(diethylamino)ethyl)amino)carbonyl)-alpha-ethyl-, ethyl ester ; Ethyl N-(2-(diethylamino)ethyl)-2-ethyl-2-phenylmalonamate ; Femamide ; Fenalamidum ; N-(2-(Diethylamino)ethyl)-2-ethyl-2-phenylmalonamic acid ethyl ester ; Phenylaethylmalonsaeure-aethylester-diaethylaminoaethyl-amid ; Malonamic acid, N-(2-(diethylamino)ethyl)-2-ethyl-2-phenyl-, ethyl ester .

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