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Name	Femoxetine hydrochloride	EINECS	N/A
CAS No.	56222-04-9	Density	N/A
PSA	N/A	LogP	N/A
Solubility	N/A	Melting Point	N/A
Formula	C₂₀H₂₅NO₂•ClH	Boiling Point	N/A
Molecular Weight	347.92	Flash Point	N/A
Transport Information	N/A	Appearance	N/A
Safety	Human toxic effects by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and HCl.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	N/A

Femoxetine hydrochloride Chemical Properties

IUPAC Name: (3R,4S)-3-[(4-Methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine hydrochloride
Synonyms of Femoxetine hydrochloride (CAS NO.56222-04-9) : (3R-trans)-3-((4-Methoxyphenoxy)methyl)-1-methyl-4-phenylpiperidine hydrochloride ; Femoxetine HCl ; Femoxetine hydrochloride ; Malexil ; Piperidine, 3-((4-methoxyphenoxy)methyl)-1-methyl-4-phenyl-, hydrochloride, (3R-trans)-
InChI: InChI=1/C20H25NO2.ClH/c1-21-13-12-20(16-6-4-3-5-7-16)17(14-21)15-23-19-10-8-18(22-2)9-11-19;/h3-11,17,20H,12-15H2,1-2H3;1H/t17-,20-;/m1./s1
CAS NO:56222-04-9
Molecular Formula:C₂₀H₂₆ClNO₂
Molecular Weight :347.8789
Molecular Structure :
Flash Point: 142.6 °C
Enthalpy of Vaporization: 69.46 kJ/mol
Boiling Point: 437.9 °C at 760 mmHg
Vapour Pressure: 7.19E-08 mmHg at 25°C

Femoxetine hydrochloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	45mg/kg (45mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
mouse	LD50	oral	1408mg/kg (1408mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
mouse	LD50	subcutaneous	723mg/kg (723mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat	LD50	intravenous	48mg/kg (48mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat	LD50	oral	1473mg/kg (1473mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
rat	LD50	subcutaneous	1120mg/kg (1120mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	European Journal of Pharmacology. Vol. 32, Pg. 108, 1975.
women	TDLo	oral	2576mg/kg/23W (2576mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"	Acta Pharmacologica et Toxicologica. Vol. 58, Pg. 253, 1986.

Femoxetine hydrochloride Safety Profile

Human toxic effects by ingestion. Experimental reproductive effects. When Femoxetine hydrochloride (CAS NO.56222-04-9) is heated to decomposition ,it emits toxic fumes of NO_x and HCl.

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