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Fenoldopam

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Name

Fenoldopam

EINECS 266-612-7
CAS No. 67227-56-9 Density 1.38 g/cm3
PSA 72.72000 LogP 3.06320
Solubility DMSO: >12 mg/mL Melting Point N/A
Formula C16H16ClNO3 Boiling Point 522.6 ºC at 760 mmHg
Molecular Weight 305.761 Flash Point 269.9 ºC
Transport Information N/A Appearance N/A
Safety S22;S26;S36/37/39 Risk Codes R22;R36;R42/43   
Molecular Structure Molecular Structure of 67227-56-9 (Fenoldopam) Hazard Symbols
Synonyms

(?à)-Fenoldopam;(?à)-SKF 82526;Fenoldopam;SKF82526;

Article Data 2

Fenoldopam Specification

   Fenoldopam (CAS NO.67227-56-9) is a synthetic benzazepine derivative drug that acts as a selective peripheral dopamine D1 receptor weak partial agonist.And it is used as an antihypertensive agent postoperatively, and via IV to treat hypertensive crisis, and also can be called Corlopam ; 6-Chloro-7,8-dihydroxy-1-p-hydroxyphenyl-2,3,4,5-tetrahydro-1H-3-benzazepine ; 1H-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)- ;and 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol .By activating peripheral D1 receptors, it causes arterial/arteriolar vasodilation leading to a decrease in blood pressure.Adverse effects include flushing, headache, hypotension, reflex tachycardia, angina, and increased intraocular pressure.
  Fenoldopam mesylate (CAS NO.67227-56-9) is irritating to the eyes, so if it is in case of contact with eyes, rinse immediately with plenty of water and seek medical advice; It is may cause sensitization by inhalation and by skin contact, so  people must Wear suitable protective clothing ,suitable gloves and eye/face protection.

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