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Fluphenazine

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Name

Fluphenazine

EINECS 200-702-9, 205-674-1, 22
CAS No. 69-23-8 Density 1.272g/cm3
PSA 55.25000 LogP 4.24890
Solubility Melting Point 268-274℃
Formula C22H26 F3 N3 O S Boiling Point 568.3°C at 760 mmHg
Molecular Weight 437.529 Flash Point 297.5°C
Transport Information small Appearance white crystalline powder
Safety Risk Codes 11-23/24/25-39/23/24/25
Molecular Structure Molecular Structure of 69-23-8 (FLUPHENAZINE) Hazard Symbols 6.1 (Packing Group: III) UN NO.
Synonyms

1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine;4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol;Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine;Ftorphenazine; Pacinol; Phthorphenazine; S 94; SQ 4918; Siqualine; Siqualon;Triflumethazine; Vespazine

Article Data 7

Fluphenazine Chemical Properties

IUPAC Name: 2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
The MF of Triflumethazine (CAS NO.69-23-8) is C22H26F3N3OS.

           
The MW of Triflumethazine (CAS NO.69-23-8) is 437.52.
Synonyms of Triflumethazine (CAS NO.69-23-8): 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)- ; 2-(Trifluoromethyl)-10-[3-[1-(b-hydroxyethyl)-4-piperazinyl]propyl]phenothiazine ; 1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine
Index of Refraction: 1.579 
Density: 1.272 g/ml
Flash Point: 297.5 °C
Boiling Point: 568.3 °C

Fluphenazine Uses

 Triflumethazine (CAS NO.69-23-8) is used as chemical reagent, fine chemicals, organic synthesis reagents, pharmaceutical intermediates.

Fluphenazine Toxicity Data With Reference

1.    

orl-rat TDLo:62 mg/kg (9D pre/1-22D preg):REP

    APEPA2    Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. 257 (1967),338.
2.    

ipr-rat LD50:100 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
3.    

scu-rat LD50:640 mg/kg

    MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (2)(1967),199.
4.    

orl-mus LD50:220 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
5.    

ipr-mus LD50:89 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
6.    

ivn-mus LD50:51 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.

Fluphenazine Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F, NOx, and SOx. See also FLUORIDES.

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