Products Categories
| CAS No.: | 849217-64-7 |
|---|---|
| Name: | Foretinib (GSK1363089) |
| Molecular Structure: | |
|
|
|
| Formula: | C34H34F2N4O6 |
| Molecular Weight: | 632.664 |
| Synonyms: | N1'-[3-fluoro-4-[[6-methoxy-7-(3-morpholinopropoxy)-4-quinolyl]oxy]phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide; N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;GSK 1363089; |
| Density: | 1.373 g/cm3 |
| Boiling Point: | 828.475 °C at 760 mmHg |
| Flash Point: | 454.846 °C |
| PSA: | 116.45000 |
| LogP: | 5.98340 |
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- 926293-55-26-Bromo-2-methylpyridine-3-carboxaldehyde
- 911112-05-55-Iodo-3-(trifluoromethyl)-2-pyridinamine
What can I do for you?
Get Best Price
Specification
The Foretinib, with the CAS registry number 84951-44-0, is also called N1'-[3-fluoro-4-[[6-methoxy-7-(3-morpholinopropoxy)-4-quinolyl]oxy]phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide. And the molecular formula of the chemical is C34H34F2N4O6.
The characteristics of Foretinib are as followings: (1)ACD/LogP: 2.28; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 0.568; (4)ACD/LogD (pH 7.4): 2.12; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 22.073; (7)ACD/KOC (pH 5.5): 8.076; (8)ACD/KOC (pH 7.4): 287.841; (9)#H bond acceptors: 10; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 12; (12)Polar Surface Area: 111.25 Å2; (13)Index of Refraction: 1.649; (14)Molar Refractivity: 167.865 cm3; (15)Molar Volume: 460.799 cm3; (16)Polarizability: 66.547×10-24cm3; (17)Surface Tension: 62.159 dyne/cm; (18)Density: 1.373 g/cm3; (19)Flash Point: 454.846 °C; (20)Enthalpy of Vaporization: 120.399 kJ/mol; (21)Boiling Point: 828.475 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: COc1cc2c(ccnc2cc1OCCCN3CCOCC3)Oc4ccc(cc4F)NC(=O)C5(CC5)C(=O)Nc6ccc(cc6)F
(2)InChI: InChI=1/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
(3)InChIKey: CXQHYVUVSFXTMY-UHFFFAOYAU