- 921205-02-91,3,5-Tri(p-pyrid-3-yl-phenyl)benzene
- 921205-03-01,3,5-Tri(m-pyrid-3-yl-phenyl)benzene
- 92122-45-7Fmoc-D-Lys(Boc)-OH
- 92123-88-1Isoquinoline,1-(2-chlorophenyl)-3-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)-, hydrochloride(1:?)
- 921-26-6Phosphoramidousdichloride, N,N-bis(1-methylethyl)-
- 92128-67-1Hydrocarbons,C8-10
- 92128-82-0Laminaria, ext.
- 92128-87-5Lecithins, hydrogenated
- 92129-41-4Ribonucleic acids,transfer, phenylalanine-specific, Escherichia coli
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
Fotemustine |
EINECS | N/A |
| CAS No. | 92118-27-9 | Density | 1.37 g/cm3 |
| PSA | 107.11000 | LogP | 2.92120 |
| Solubility | N/A | Melting Point |
85° |
| Formula | C9H19 Cl N3 O5 P | Boiling Point | °Cat760mmHg |
| Molecular Weight | 315.694 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | 36/37 | Risk Codes | 40 |
| Molecular Structure |
|
Hazard Symbols | Xn |
| Synonyms |
Phosphonicacid, [1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester(9CI); Fotemustine; Muphoran; Mustophorane; S 10036 |
Fotemustine Chemical Properties
Molecular Structure of Fotemustine (CAS NO.92118-27-9):
.gif)
IUPAC Name: 1-(2-Chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea
Molecular Formula: C9H19ClN3O5P
Molecular Weight: 315.69
CAS Registry Number: 92118-27-9
Index of Refraction: 1.524
Molar Refractivity: 70.32 cm3
Molar Volume: 229.7 cm3
Surface Tension: 49.4 dyne/cm
Density: 1.37 g/cm3
Classification Code: Antineoplastic agents; Drug / Therapeutic Agent; Mutation data
Canonical SMILES: CCOP(=O)(C(C)NC(=O)N(CCCl)N=O)OCC
InChI: InChI=1S/C9H19ClN3O5P/c1-4-17-19(16,18-5-2)8(3)11-9(14)13(12-15)7-6-10/h8H,4-7H2,1-3H3,(H,11,14)
InChIKey: YAKWPXVTIGTRJH-UHFFFAOYSA-N
Fotemustine Uses
Fotemustine (CAS NO.92118-27-9) is used in the treatment of metastasising melanoma. A study has shown that Fotemustine produces over dacarbazine which improved response rates and increased survival in the treatment of disseminated cutaneous melanoma.
Fotemustine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 60mg/kg (60mg/kg) | Cancer Research. Vol. 47, Pg. 6782, 1987. |
Fotemustine Specification
Fotemustine (CAS NO.92118-27-9), its Synonyms are (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate ; Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate ; Fotemustina ; Fotemustinum ; Phosphonic acid, (1-((((2-chloroethyl)nitrosoamino)carbonyl)amino)ethyl)-, diethyl ester . Fotemustine is a nitrosourea alkylating agent.
What can I do for you?
Get Best Price
