Chemistry - An Asian Journal p. 2719 - 2723 (2019)
Update date:2022-08-04
Topics:
Otsuka, Yuji
Yamamoto, Toshihiro
Fukase, Koichi
New glycosyl donors have been developed that contained several para-substituted O-aryl protecting groups and their stereoselectivity for the glycosylation reaction was evaluated. A highly β-selective glycosylation reaction was achieved by using thioglycosides that were protected by 4-nitrophenyl (NP) groups, which were introduced by using the corresponding diaryliodonium triflate. Analysis of the stereoselectivities of several glycosyl donors indicated that the β-glycosides were obtained through an SN2-type displacement from the corresponding α-glycosyl triflate. The NP group could be removed by reduction of the nitro group and acylation, followed by oxidation with ceric ammonium nitrate (CAN).
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Doi:10.1016/j.tet.2007.12.055
(2008)Doi:10.1039/CT9048500165
(1904)Doi:10.1007/s11164-016-2678-5
(2017)Doi:10.1002/hlca.19890720418
(1989)Doi:10.1016/j.bioorg.2021.105121
(2021)Doi:10.1021/jo01065a007
(1961)