92868-25-2

Upstream product

• 49568-76-5 3-benzoylquinoxalin-2(1H)-one 
• 74-88-4 methyl iodide 
• 58876-61-2 1-methyl-4-phenyl-1H-benzo[b][1,4]diazepin-2(3H)-one 
• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 100-52-7 benzaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 613-94-5 benzoic acid hydrazide 
• 74-83-9 methyl bromide 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 1123812-22-5 5-methyl-1-(3-formylphenyl)-3-phenylimidazo[1,5-a]quinoxalin-4-one 
• 1123812-10-1 1,3-bis(5-methyl-4-oxo-3-phenylimidazo[1,5-a]quinoxalin-1-yl)benzene 

Relevant academic research and scientific papers

Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones

A novel and practical synthesis of 3-benzoylquinoxalin-2(1H)-ones from benzodiazepin-2-ones in two steps from commercially available starting materials is reported. The reaction was achieved in the presence of N-bromosuccinimide in DMSO which served both

Ring contraction in reactions of 3-benzoylquinoxalin-2-ones with 1,2-phenylenediamines. Quinoxaline-benzoimidazole rearrangement

The reactions of 3-benzoylquinoxalin-2-one and its N(1)-alkyl derivatives with 1,2-phenylenediamines were accompanied by ring contraction as a result of the quinoxaline-benzoimidazole rearrangement giving rise to 2-benzoimidazolyl- substituted quinoxalhies. The possible pathways of these reaction are discussed.

Photocatalyst-free visible light induced decarboxylative alkylation of quinoxalin-2(1H)-ones with carboxylic acids

Using commercially available and cheap carboxylic acids as alkylating reagents, a practical methodology for the visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones was developed. The reaction proceeds in the absence of metal-catalyst

Visible-Light-Promoted Switchable Synthesis of C-3-Functionalized Quinoxalin-2(1H)-ones

A visible-light-promoted synthesis of quinoxalin-2(1H)-ones has been developed using 9-mesityl-10-methylacridinium perchlorate as an organo-photocatalyst. The atmosphere-controlled method (Ar/air) enabled the selective synthesis of hydroxyl- and acyl-containing quinoxalin-2(1H)-ones under mild reaction conditions without the use of any metal catalysts or toxic reagents. A fluorescent labelling experiment showed that hydroxyl-containing quinoxalin-2(1H)-ones may have utility in various biological applications as potent fluorophores. (Figure presented.).

Eosin Y as a direct hydrogen-atom transfer photocatalyst for the C3-H acylation of quinoxalin-2(1H)-ones

Visible light promoted eosin Y catalyzed selective C3-H acylation of quinoxalin-2(1H)-ones has been developed in a green and sustainable manner. In contrast to the conventional anionic eosin Y-based photoredox process, neutral eosin Y acts as the actual c

Acyl Radicals from α-Keto Acids: Metal-Free Visible-Light-Promoted Acylation of Heterocycles

A general and metal-free visible-light-induced decarboxylative arylation procedure at room temperature was described for the construction of acylated heterocyclic derivatives, such as benzimidazo/indolo[2,1-a]isoquinolin-6(5H)-ones, aroylazaspiro[4.5]trie

Metal-free C3-H acylation of quinoxalin-2(1: H)-ones with α-oxo-carboxylic acids

Direct C3-H acylation of quinoxalin-2(1H)-ones with α-oxocarboxylic acids under thermo conditions promoted by PIDA has been achieved in a moderate to good yield in a very fast manner. Mechanistic study revealed that the reaction proceeds via a radical pro

Photocatalytic preparation method of 3-acyl quinoxalinone compound

The invention discloses a method for preparing 3-acyl quinoxalinone, and particularly relates to a method for preparing a 3-acyl quinoxalinone compound by utilizing photocatalysis technology. The preparation method specifically comprises the following ste

Visible-light-induced decarboxylative acylation of quinoxalin-2(1: H)-ones with α-oxo carboxylic acids under metal-, strong oxidant- And external photocatalyst-free conditions

A mild and eco-friendly visible-light-induced decarboxylative acylation of quinoxalin-2(1H)-ones and α-oxo carboxylic acids with ambient air as the sole oxidant at room temperature was established. The reaction proceeded efficiently without any metal cata

Photoredox Catalyst Free, Visible Light-Promoted C3?H Acylation of Quinoxalin-2(1H)-ones in Water

A method for the synthesis of 3-acyl quinoxalin-2(1H)-ones through visible-light promoted decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones was developed. The reaction was performed in aqueous phase and photoredox catalyst was not required to run the process. (Figure presented.).