Tetrahedron Letters p. 5537 - 5540 (1993)
Update date:2022-08-03
Topics:
Garigipati, Ravi S.
Sorenson, Margaret E.
Erhard, Karl F.
Adams, Jerry L.
Racemic hydroxyureas can be efficiently resolved on a preparative scale using (4S)- 4-benzyl-2-oxazolidine-3-carbonyl chloride 3.The resulting carbamates can be separated by chromatography and hydrolysis of these diastereomers yields enantiomerically pure hydroxyureas.
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