Journal of Medicinal Chemistry p. 5047 - 5052 (1996)
Update date:2022-08-05
Topics:
Takami, Hitoshi
Koshimura, Hirokazu
Kishibayashi, Nobuyuki
Ishii, Akio
Nonaka, Hiromi
Aoyama, Shiro
Kase, Hiroshi
Kumazawa, Toshiaki
A series of indole derivatives with varied substituents on the α,β- unsaturated double bond were synthesized and evaluated for their ability to inhibit rat prostatic 5α-reductase. Compounds possessing an ethyl substituent at the β-position of the double b
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