A new access to isoindolo[2,1-b] [2,4]benzodiazepines through an N-acyliminium ion - Amide cyclization

DOI: 10.1016/S0040-4039(97)00539-X

Source and publish data:

Tetrahedron Letters p. 2985 - 2988 (1997)

Update date:2022-08-03

Topics:

Authors:

Pigeon, Pascal

Decroix, Bernard

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Article abstract of DOI:10.1016/S0040-4039(97)00539-X

Isoindolo[2,1-b][2,4]benzodiazepines 11a-c were synthesized from hydroxylactam-acid 5 when it was treated successively with thionyl chloride, ammonia (or an alkylamine) and p-toluenesulfonic acid.

Full text of DOI:10.1016/S0040-4039(97)00539-X

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