Journal of Medicinal Chemistry p. 1401 - 1417 (1993)
Update date:2022-08-03
Topics: Oxazoles Receptor antagonists Thromboxane A2 Interphenylene
Misra, Raj N.
Brown, Baerbel R.
Sher, Philip M.
Patel, Manorama M.
Hall, Steven E.
et al.
A series of interphenylene 7-oxabicyclo<2.2.1>heptane oxazoles (2) were prepared and evaluated for their thromboxane (TxA2) antagonistic activity in vitro and duration of action in vivo.Examination of the carboxyl side chain indicated that the
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