The Reaction of 4-Phenyl-2-azetidinone with Aldehydes

DOI: 10.1002/ardp.19863190305

Source and publish data:

Archiv der Pharmazie p. 216 - 226 (1986)

Update date:2022-08-02

Topics:

Authors:

Bergmann, Hans-Joachim

Otto, Hans-Hartwig

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Article abstract of DOI:10.1002/ardp.19863190305

The title compound 1 reacts with aliphatic aldehydes to yield N-(1-hydroxyalkyl) derivatives 5, which can be dehydrated to N-vinyl-β-lactams 6.The reaction of 1 with aromatic aldehydes gives amidols 9, from which the derivatives 10 are obtained by acylation.

Full text of DOI:10.1002/ardp.19863190305

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