ASYMMETRIC SYNTHESIS VII1: ENANTIOSPECIFIC PREPARATION OF β-AMINOALCOHOLS FROM THE N-CYANOMETHYL-4-PHENYL-1,3-OXAZOLIDINE SYNTHON

Article abstract of DOI:10.1016/S0040-4039(01)84595-0

(-)-N-cyanomethyl-4-phenyl-1,3-oxazolidine 1 has been investigated as chiral template for the enantiospecific synthesis of β-aminoalcohols. (-)-2(R)-hydroxy-3(S)-nonylamine 5a was chosen as a target molecule of the new method.