Angewandte Chemie - International Edition p. 3381 - 3384 (2008)
Update date:2022-09-26
Topics:
Goldup, Stephen M.
Leigh, David A.
Lusby, Paul J.
McBurney, Roy T.
Slawin, Alexandra M. Z.
(Chemical Equation). Taking the Michael: Rotaxanes (see structure) and molecular shuttles are prepared in up to 99% yield by successive Pd II-promoted 1,4-conjugate additions in a one-pot four-component assembly process. This process represents the first active template reaction in which the template motif is retained in the interlocked product.
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