Journal of the Chemical Society. Chemical communications p. 1229 - 1230 (1985)
Update date:2022-08-04
Topics:
Meij, Paul F. C. van der
Lohmann, Ruth D.
Waard, Eduard R. de
Chen, Tjoe B. R. A.
Pandit, Upendra K.
Reaction of 6-aminouracil derivatives with imidazolidines (methylenetetrahydrofolate models), in the presence of acid, gives an exocyclic methylene intermediate which reacts with nucleophiles present in the mixture or can be reduced to a thymine derivative.
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