Metalated Allylaminosilane: A New, Practical Reagent for the Stereoselective α-Hydroxyallylation of Aldehydes to Erythro-1,2-diol Skeletons

DOI: 10.1021/jo00381a053

Source and publish data:

Journal of Organic Chemistry p. 957 - 958 (1987)

Update date:2022-08-03

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Authors:

Tamao, Kohei

Nakajo, Eiji

Ito, Yoshihiko

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Article abstract of DOI:10.1021/jo00381a053

A zinc reagent derived from allyl(diisopropylamino)dimethylsilane reacts with aldehydes regio- and stereoselectively to form erythro-3-silyl-1-alken-4-ols, which are further transformed into erythro-1-alkene-3,4-diols by hydrogen peroxide oxidation of the

Full text of DOI:10.1021/jo00381a053

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Product name:{Dimethyl-[(R)-1-((S)-phenyl-trimethylsilanyloxy-methyl)-allyl]-silanyl}-diisopropyl-amine

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