Metalated Allylaminosilane: A New, Practical Reagent for the Stereoselective α-Hydroxyallylation of Aldehydes to Erythro-1,2-diol Skeletons

DOI: 10.1021/jo00381a053

Source and publish data:

Journal of Organic Chemistry p. 957 - 958 (1987)

Update date:2022-08-03

Topics:

Authors:

Tamao, Kohei

Nakajo, Eiji

Ito, Yoshihiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00381a053

A zinc reagent derived from allyl(diisopropylamino)dimethylsilane reacts with aldehydes regio- and stereoselectively to form erythro-3-silyl-1-alken-4-ols, which are further transformed into erythro-1-alkene-3,4-diols by hydrogen peroxide oxidation of the

Full text of DOI:10.1021/jo00381a053

Products guided by the article

Product name:{Dimethyl-[(R)-1-((S)-phenyl-trimethylsilanyloxy-methyl)-allyl]-silanyl}-diisopropyl-amine

Cas No:106948-16-7

R&D Labs maybe for 106948-16-7

Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
Shanghai Hanshare Industry Co.,Ltd.

Contact:86 21 20960688

Address:RM902-903,Building E, Wanda Plaza,No.26,Zhoukang Road, Pudong District, Shanghai, China
JIAXING SUNS INTERNATIONAL TRADE CO LTD

Contact:18367306858

Address:No.123,Huixin Avenue,Huimin Dist
Shenzhen Ejion Biotechnology Co., Ltd

Contact:86--13823686453

Address:RM1336, Block C, QingHu Technology Park,Longhua District,Shenzhen City

Relevant to this article

Enantioselective Stetter Reactions Catalyzed by Bis(amino)cyclopropenylidenes: Important Role for Water as an Additive

Doi:10.1021/acs.orglett.0c03879
(2021)
Synthesis of Deoxyfrenolicin and Nanaomycin A

Doi:10.1021/jo00383a018
(1987)
Total synthesis of neolaulimalide and isolaulimalide

Doi:10.1021/ol802075v
(2008)
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2- chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses

Doi:10.1021/jm800856c
(2008)
Synthesis and antimalarial effects of 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-6- alkylphenols and their N(ω)-oxides

Doi:10.1021/jm00388a027
(1987)
N-methyl derivatives of the 5-HT₂ agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane

Doi:10.1021/jm00388a032
(1987)

Article Doi