Synthetic Communications p. 3375 - 3389 (2008)
Update date:2022-08-05
Topics:
Shaterian, Hamid Reza
Hosseinian, Asghar
Ghashang, Majid
Silica gel-supported polyphosphoric acid (PPA-SiO2) was found to be an efficient catalyst for the multicomponent condensation reaction of aryl aldehydes, 2-naphthol, and urea or amides to afford the corresponding 1-amidoalkyl-2-naphthols in good to excellent yields. This new approach consistently had short reaction times, high conversions, clean reaction profiles, and simple experimental and workup procedures. Copyright Taylor & Francis Group, LLC.
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(2008)