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113-24-6

Basic Information
CAS No.: 113-24-6
Name: Sodium pyruvate
Article Data: 22
Molecular Structure:
Molecular Structure of 113-24-6 (Sodium pyruvate)
Formula: C3H3NaO3
Molecular Weight: 110.045
Synonyms: Propanoicacid, 2-oxo-, sodium salt (9CI);Pyruvic acid, sodium salt (7CI,8CI);Sodiumpyruvate;Sodium a-ketopropionate;
EINECS: 204-024-4
Density: 1.267 g/cm3
Melting Point: >300 °C(lit.)
Boiling Point: 165 °C at 760 mmHg
Flash Point: 54.3 °C
Solubility: water: 100 mg/mL
Appearance: White to slightly yellow crystalline powder
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 36/37/39-26-24/25
PSA: 57.20000
LogP: -1.67470
Synthetic route
127-17-3

2-oxo-propionic acid

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium formate In ethyl acetate97%
With sodium acetate In ethyl acetate94%
With sodium hydroxide; ethanol; water
79-41-4

poly(methacrylic acid)

113-24-6

sodium pyruvate

Conditions
ConditionsYield
Stage #1: poly(methacrylic acid) With ozone In methanol; dichloromethane at -78℃;
Stage #2: With dimethylsulfide In methanol; dichloromethane at -78 - 20℃;
Stage #3: With sodium hydroxide In water
92%
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
Stage #1: ethyl 2-hydroxypropionate With 9-azabicyclo<3.3.1>nonane-N-oxyl; dihydrogen peroxide In ethyl acetate at 10 - 40℃; for 3h;
Stage #2: With sodium carbonate In water; ethyl acetate at 20℃; for 1h; pH=3 - 4; Reagent/catalyst; Temperature;
55%
56-41-7

L-alanin

114-76-1

sodium phenylphyruvate

A

150-30-1

Phenylalanine

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With acetate buffer; N(1+)C5His2C16; PL(1+)2C16; copper(II) perchlorate In water at 30℃; for 48h; Kinetics;
21593-77-1, 49621-03-6

S-allyl cysteine

A

2179-57-9

diallyl disulphide

B

539-86-6

allicin

C

29418-05-1

bis-2-propenyl thiosulfonate

D

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With nitrogen(II) oxide In water for 24h; Ambient temperature; Yield given. Yields of byproduct given;
44300-97-2

sodium enol pyruvate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide; iodine; potassium iodide In water at 25℃; Rate constant; Equilibrium constant; other base as reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; enolization;
43165-43-1

sodium pyruvate hydrate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; Rate constant; Equilibrium constant; other bases or acids reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; hydration;
312-85-6

sodium lactate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide; lead(II) nitrate In water Product distribution; modified platinum electrode by lead ad-atoms, effect of pyruvate concentration;
With sodium ruthenate(VI); hexacyanoferrate(III); sodium perchlorate; sodium hydroxide at 30℃; Kinetics; Mechanism;
5824-58-8

3‐phosphopyruvate

A

113-24-6

sodium pyruvate

B

phosphate

phosphate

Conditions
ConditionsYield
With acetate buffer In water at 75℃; Mechanism; Kinetics; Thermodynamic data; different buffers: pH 0.59 to 8.32; kH/kD; different temp.; Ea, ΔH(excit.), ΔS(excit.);

Sodium; (2S,4S,5R,6S)-6-(1,2-dihydroxy-ethyl)-2,4,5-trihydroxy-tetrahydro-pyran-2-carboxylate

A

608-47-9

β-D-lyxopyranose

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With N-acetylneuraminic acid aldolase at 37℃;
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Chemistry

IUPAC Name: Sodium 2-oxopropanoate
Synonyms of of Sodium Pyruvate (CAS NO.113-24-6): 2-Oxopropanoate de sodium ; Natrium-2-oxopropanoat ; Propanoic acid, 2-oxo-, sodium salt ; Propanoic acid, 2-oxo-, sodium salt (1:1) ; Sodium 2-oxopropanoate
Molecular Structure:
Molecular Formula: C3H3NaO3
Molecular Weight: 110.04
CAS NO : 113-24-6
EINECS : 204-024-4
BRN : 3568341
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 54.37 Å2
Flash Point: 54.3 °C
Enthalpy of Vaporization: 44.28 kJ/mol
Boiling Point: 165 °C at 760 mmHg
Vapour Pressure: 0.968 mmHg at 25°C
Melting Point: >300 °C(lit.)
Density: 1.267g/cm3
Refractive index: 1.426-1.43
Storage temp: 2-8°C
Solubility: H2O: 100 mg/mL
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance:White to slightly yellow crystalline powder
Product Categories of Sodium Pyruvate (CAS NO.113-24-6): FINE Chemical & INTERMEDIATES;PyruvicAcidSeries;Hybridoma Media SupplementsCell Culture;Hybridoma Platform;Miscellaneous Reagents and SupplementsNeural Stem Cell Biology;Neural Stem Cell Isolation/Expansion;Reagents and Supplements;Serum-free Media;Supplements/Reagents

Uses

 Sodium Pyruvate (CAS NO.113-24-6) is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups.

Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 36/37/39-26-24/25
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S24/25: Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
WGK Germany: 3
HS Code: 29183000