
Journal of Organic Chemistry p. 2433 - 2442 (1987)
Update date:2022-07-30
Topics:
Dijkstra, Pieter J.
Hertog, Herman J. den
Steen, Bart J. van
Zijlstra, Sietze
Skowronska-Ptasinska, Maria
The effect of variation of the rigid part of the parent Cram hemispherand 1a on the preorganization of the macrocyclic cavity has been studied.Four novel 18-membered hemispherands (3,4a-c)have been synthesized via a novel multistep route using 2,6-di- and
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