Tetrahedron Letters p. 4957 - 4960 (1986)
Update date:2022-08-05
Topics:
Evans, David A.
Sjogren, Eric B.
Bartroli, Javier
Dow, Robert L.
Aldol addition reaction of the crotonate imides 1 and 2 affords the adducts 3 and 4 with high diastereoselection.Subsequent removal of the chiral auxiliary can be effected in good yield to provide a number of synthetically useful intermediates.
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Doi:10.1007/BF00473485
(1986)Doi:10.1007/BF00478131
(1986)Doi:10.1002/mrc.4261
(2015)Doi:10.1021/jo00227a008
(1987)Doi:10.1021/jo00227a003
(1987)Doi:10.1039/d0gc03141k
(2020)