Journal of Organic Chemistry p. 2976 - 2983 (1991)
Update date:2022-07-31
Topics:
Chida, Noritaka
Ohtsuka, Masami
Nakazawa, Keiichi
Ogawa, Seiichiro
The first total synthesis of the antibiotic (-)-hygromycin A (1) has been achieved by a coupling reaction of the sugar moiety (2) and the cyclitol moiety (3).Both components were synthesized in homochiral forms starting from D-glucose.This synthesis fully
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(1991)Doi:10.1021/jo00180a026
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(2018)
