Facile preparation of a 4-substituted [2,6-14C]pyridine: Synthesis of [14C]SK and F 105809

Article abstract of DOI:10.1002/(SICI)1099-1344(199608)38:8<761::AID-JLCR887>3.0.CO;2-2

[¹⁴C]Formaldehyde was used in a nucleophile-assisted iminium ion cyclization with N-benzyl-3-butynylamine to provide N-benzyl-4-iodo-1,2,5,6-tetrahydro[2, 6-¹⁴C₂]pyridine. Palladium-catalyzed coupling of this vinyl iodide