
Chemistry Letters p. 445 - 448 (1987)
Update date:2022-07-29
Topics: Synthesis Chiral Intermediates Experimental 2-azetidinone Thienamycin
Ito, Yoshio
Terashima, Shiro
The title thienamycin intermadiate was efficiently synthesized from (S)-ethyl lactate (3) by subjecting (3S,4S)-32-acetyl-4-<(S)-1-benzyloxyethyl>-2-azetidinone readily obtainable from 3, to sequential reactions in which base catalyzed elimination and reg
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