SYNTHESIS OF 3-(INDOL-2-YL)-PROPENOATE DERIVATIVES OF TRYPTAMINE, VALUABLE INTERMEDIATES FOR THE PREPARATION OF INDOLE ALKALOIDS

DOI: 10.1016/S0040-4039(00)96233-6

Source and publish data:

Tetrahedron Letters p. 2879 - 2882 (1987)

Update date:2022-07-29

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Authors:

Bailey, Patrick D.

Hollinshead, Sean P.

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Article abstract of DOI:10.1016/S0040-4039(00)96233-6

A simple three step route to 3-(indol-2-yl)-propenoate derivatives of tryptamine has been developed, involving the base-induced ring-opening of protected tetrahydro-β-carbolines that result from a modified Pictet-Spengler reaction.

Full text of DOI:10.1016/S0040-4039(00)96233-6

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