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9004-61-9

Basic Information
CAS No.: 9004-61-9
Name: Hyaluronic acid
Article Data: 6
Molecular Structure:
Molecular Structure of 9004-61-9 (Hyaluronic acid)
Formula: (C14H21NO11)n
Molecular Weight: 403.31
Synonyms: Hyaluronate;See also Hyaluronic acid;[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n;Mucoitin;Luronit;Hyaluronan;HYALURONIC ACID SODIUM SALT;Hyaluronic acid, HA;Hyaluronic Acid Cosmetic Grade, pharm grade and food grade;Hydluronic acid;Hyaluronic acid(Sodium Hyaluronate);Hyaluronic acid(gel);Hyaluronic Acid Cross-Linkers;hyaluroni acid(food grade);hyaluronic acid(food grade);Hyaluronic acid from bovine vitreous humor;
EINECS: 232-678-0
Density: 1.78 g/cm3
Boiling Point: 1274.4oC at 760 mmHg
Flash Point: 724.5oC
Solubility: Soluble in water.
Appearance: White powder
Hazard Symbols:
Safety: 22-24/25
PSA: 399.71000
LogP: -8.49480
Raw Materials
9067-32-7
Downstream Products
9067-32-7
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    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

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  • Hyaluronic acid (> 1600kDa)/kg

  • Casno:

    9004-61-9

    Hyaluronic acid (> 1600kDa)/kg

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 200.0-200.0

    Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

    Hubei Hanways Pharmchem Co.,Limited is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. Now we

  •  HANWAYS CHEMPHARM CO.,LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18502787239(whatsapp)

    Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

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  • Hyaluronic acid (SODIUM SALT)9004-61-9//9067-32-7

  • Casno:

    9004-61-9

    Hyaluronic acid (SODIUM SALT)9004-61-9//9067-32-7

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product Name: Hyaluronic acid Synonyms: [BETA-SODIUM-GLUCONATE-(1,3)-BETA-N-ACETYL-D-GLUCOSAMINE-1,4-]N;COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4] SODIUM SALT;HYALURONIC ACID NA-SALT;HYALURONIC ACID, SODIUM SALT, STRE

    SHANGHAI MINSTAR CHEMICAL CO., LTD. is a leading, experienced, professional supplier of API & intermediates, plant extract, food additive, fine chemicals and industry chemicals, et

  •  Shanghai Minstar Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-18019205509

    Address:BUILDING 8, NO.1098, CHUANSHA ROAD, SHANGHAI, CHINA

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Specification

The Hyaluronic acid is a polymer of disaccharides composed of D-glucuronic acid and D-N-acetylglucosamine with molecular formula (C14H21NO11)n. With cas registry number of 9004-61-9, this chemcial is also known as Hyaluronan; HA. Besides, it also has other registry numbers wich include 165324-65-2, 29382-75-0, 37243-73-5, and 9039-38-7. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions.

Physical properties about Hyaluronic acid are: (1)ACD/LogP: -1.131; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): -3.85; (4)ACD/LogD (pH 7.4): -4.83; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00 ; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 12; (10)#H bond donors: 7; (11)#Freely Rotating Bonds: 10; (12)Flash Point: 432.5 °C ; (13)Enthalpy of Vaporization: 131.19 kJ/mol; (14)Boiling Point: 791.6 °C at 760 mmHg; (15)Vapour Pressure: 5.77E-29 mmHg at 25°C

Preparation of Hyaluronic acid: Hyaluronic acid is derived from hyalos (Greek for vitreous) and uronic acid because it was first isolated from the vitreous humour and possesses a high uronic acid content. It is synthesized by a class of integral membrane proteins called hyaluronan synthases, of which vertebrates have three types: HAS1, HAS2, and HAS3.

Uses of Hyaluronic acid: this compound is naturally found in many tissues of the body, such as skin, cartilage, and the vitreous humour. It is therefore well suited to biomedical applications targeting these tissues. Thus, it can be used as a common ingredient in skin care products which is considered as the natural molsturlzlng factor. It can be added to almost any cosmetics, widely used in cream, lotion, lotion, essence, facial cleanser, shower gel, shampoo, hair extension agent, mousse, lipstick and other cosmetics with adding amount 0.05 -0.5% in general. Besides, it is also used in treatment of articular disorders in horses, particularly those in competition or heavy work.

You can still convert the following datas into molecular structure:
(1)InChI: InChI=1/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18?,19?,20+,21+,22+,25-,26+,27-,28-/m1/s1;
(2)Smiles: O([C@@H]1[C@H]([C@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3O)CO)O)NC(C)=O)[C@@H]([C@H]2O)O)C(O)=O)O[C@@H]([C@H]1O)CO)NC(C)=O)[C@@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)C(O)=O