Synthesis p. 418 - 420 (1987)
Update date:2022-09-26
Topics:
Nakonieczna, Lucja
Chimiak, Andrzej
The concept of transient hydroxylamine oxygen protection for the unambiguous synthesis of N-hydroxyamides has been applied in the amino acid field.First, hydroxylamines 1 were silylated in pyridine with chlorotrimethylsilane; then 2 was immediately N-acylated with mixed anhydride 3 of a protected amino acid or peptide; and finally, the O-trimethylsilyl protection was removed during the isolation procedure giving pure N-hydroxyamides 5.
View MoreShantou Baokang Pharmaceutical Co., Ltd.
Contact:+86-754-88873487
Address:5/F B Block Huangshan Bldg Huangshan Rd Shantou
Melone Pharmaceutical Co., ltd
Contact:+86-411 82593920, 82593631
Address:No 232, JInma Roda, Development Zone, Dalian, China
website:http://www.jairadhesales.com
Contact:0091-79-26431096
Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
Contact:+86-134-5286-9121
Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Anhui New Star Pharmaceutical Development Co., Ltd
Contact:013956922763
Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China
Doi:10.1016/S0040-4039(00)96090-8
(1987)Doi:10.1016/S0040-4039(00)83868-X
(1986)Doi:10.1021/jm9014857
(2010)Doi:10.1016/j.tet.2009.01.013
(2009)Doi:10.1055/s-0028-1087672
(2009)Doi:10.1002/chem.202101459
(2021)
