Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones

DOI: 10.1016/j.bmc.2008.12.008

Source and publish data:

Bioorganic and Medicinal Chemistry p. 460 - 466 (2009)

Update date:2022-07-30

Topics:

Authors:

Dekker, Frank J.

Ghizzoni, Massimo

van der Meer, Nanette

Wisastra, Rosalina

Haisma, Hidde J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmc.2008.12.008

Small molecule HAT inhibitors are useful tools to unravel the role of histone acetyl transferases (HATs) in the cell and have relevance for oncology. We present a systematic investigation of the inhibition of the HAT p300/CBP Associated Factor (PCAF) by i

Full text of DOI:10.1016/j.bmc.2008.12.008

Products guided by the article

Product name:benzyl [2-(5-chloro-3-oxoisothiazol-2(3H)-yl)ethyl]carbamate

Cas No:1134642-89-9

R&D Labs maybe for 1134642-89-9

KA-SHING Business Trade Macau Co., Ltd.

Contact:00853-28430045

Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
LIDE PHARMACEUTICALS LIMITED

website:http://www.lidepharma.com

Contact:+86-25-58409506

Address:Chungking Express Nos.36 Nathan Road，Kowloon, HK
Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China

Relevant to this article

N-HALOAMIDINES.VI. REACTION OF N-CHLORO-N'-BENZENESULFONYLBENZAMIDINES WITH ENAMINES.

Doi:10.1016/S0040-4020(01)86920-9
(1987)
Reactions of diazo compounds with alkenes catalysed by [RuCl(cod)(Cp)]: Effect of the substituents in the formation of cyclopropanation or metathesis products

Doi:10.1002/chem.200801211
(2009)
Effect of N-Bromosuccinimide (NBS) and Other N-Brominating Agents on the Bromination of α,β-Unsaturated Ketones in Methanol

Doi:10.1021/jo00245a014
(1988)
Friedel-Crafts Alkylation of Aromatics by TiCl ₄ -Promoted Ring Cleavage of 3-Arylcyclobutanones

Doi:10.1055/s-0036-1591497
(2018)
Convenient synthesis of a building-block derivative of nigerose

Doi:10.1016/0008-6215(87)80151-9
(1987)
Synthesis of dibekacin (3',4'-dideoxykanamycin B) from D-glucosamine and D-glucose.

Doi:10.1248/cpb.35.2136
(1987)

Article Doi