Reductive Cleavage of the O-C(8) Bond in 5'-O,8-Cycloadenosines. Intramolecular Protection of the 8-Position and the 5'-Hydroxy Group in Adenosines

DOI: 10.1039/c39870001298

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1298 - 1299 (1987)

Update date:2022-08-04

Topics:

Authors:

Sako, Magoichi

Saito, Takao

Kameyama, Keiji

Hirota, Kosaku

Maki, Yoshifumi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39870001298

Upon treatment with NaBH3CN in acetic acid at ambient temperature, N⁶-acyl-5'-O,8-cycloadenosines (1) with or without carbon functional groups on the 2-position undergo exclusively a reductive O-C(8) bond cleavage to give the corresponding N View More

Full text of DOI:10.1039/c39870001298

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:N⁶-benzoyl-7,8-dihydro-2',3'-O-isopropylideneadenosine

Cas No:114743-94-1

R&D Labs maybe for 114743-94-1

JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

website:http://www.xypharm.com/

Contact:+86-515-84383317

Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China
NingBO Hong Xiang Biochem.Co.Ltd

website:http://www.hxbiochem.com

Contact:0574-66003444

Address:Ning Bo Bei Lun
Yangling Ciyuan biotech Co., Ltd.

Contact:86-15802970736

Address:2-1804, International Park Mansion, No.2, South Fengdeng Road, Lianhu District
Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China

Relevant to this article

Simple primary β-amino alcohol catalyzed enantioselective Diels-Alder reaction of 3-hydroxy-2-pyridones

Doi:10.1016/j.tetlet.2016.11.030
(2016)
Reactions of 1,1-Diphenylethylene and Its Derivatives with Tris(p-bromophenyl)aminium Hexachloroantimonate

Doi:10.1246/cl.1987.2251
(1987)
Improved protection and esterification of a precursor of the taxotere and taxol side chains

Doi:10.1016/S0040-4039(00)79128-3
(1992)
Synthesis of propyne iminium triflates by vacuum thermolysis of 3- trifloxypropene iminium triflates: Scope and some limitations

Doi:10.1055/s-1994-25463
(1994)
Doi:10.1055/s-1978-24846
(1978)
Yttria-zirconia-based Lewis acid catalysis of the Biginelli reaction: An efficient one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones

Doi:10.1080/00397910802519174
(2009)

Article Doi