SYNTHESIS OF (R)-1-BENZYLOXY-3-BUTEN-2-OL- A POTENTIAL CHIRAL SYNTHON FROM L-(+)-TARTARIC ACID: ITS APPLICATIONS IN NATURAL PRODUCT SYNTHESES

Article abstract of DOI:10.1016/S0040-4039(00)96898-9

A practical synthesis of (R)-3-butene-1,2-diol derivatives from (R,R)-tartaric acid and their applications for the syntheses of (R)-ethyl-5-benzoyloxy-5-formyl pentanoate (2), a useful synthon for the preparation of arachidonic acid metabolites and (R)-γ-caprolactone (3), a pheromone of Trogoderma species, are described.