
Tetrahedron Letters p. 4199 - 4202 (1987)
Update date:2022-07-29
Topics:
Baeckvall, J. E.
Renko, Z. D.
Bystroem, S. E.
A general method for the transformation of 1,3-cycloheptadienes to tropane alkaloid derivatives was developed.The procedure was applied to the stereocontrolled synthesis of the exo- and endo-tropanol derivatives 1 and 2.The approach is based on a dual stereocontrol in the 1,4-functionalization of conjugated dienes.
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