Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on α1-adrenoreceptor blocking activity

DOI: 10.1021/jm00120a009

Source and publish data:

Journal of Medicinal Chemistry p. 2300 - 2304 (1988)

Update date:2022-08-04

Topics:

Authors:

Pigini Pigini

Brasili Brasili

Giannella

Giardina

Gulini Gulini

Quaglia Quaglia

Melchiorre

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Article abstract of DOI:10.1021/jm00120a009

Several analogues of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-1,4-benzodioxan (WB 4101, 1) were prepared and evaluated for their blocking activity on α₁- and α₂-adrenoreceptors in the isolated rat vas deferens. The results we

Full text of DOI:10.1021/jm00120a009

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