Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids

Article abstract of DOI:10.1021/jm00167a015

9-Oxoxanthene-4-acetic acids are a class of antitumor agents effective against the mouse colon adenocarcinoma 38 in vivo. Within this class, a series of derivatives bearing a wide variety of substituents at the 5-position have been prepared and evaluated.