Tetrahedron p. 2037 - 2042 (1986)
Update date:2022-09-26
Topics:
Agami, Claude
Puchot, Catherine
Optically active octalones result from dehydration of the corresponding racemic β-ketols catalyzed by (S)-phenylalanine or (S)-proline.According to the nature of the amino acid, opposite enantioselectivities were observed during the kinetic resolutions.Catalysis by proline leads to higher enantiomeric excesses and occurs with greater discrimination between different substrates.A mechanism involving an intramolecular hydrogen transfer mediated by the amino-acid carboxylate group is consistent with the observed selectivities.
View MoreContact:+86-731-84427351
Address:154 JIANXIANG SOUTH ROAD
Hubei Lansun Biochemical Pharmaceutical Co., Ltd
Contact:714-6395977
Address:No. 81 Pengcheng Avenue, economic and technological development zone, Huangshi City, Hubei Province,China
Contact:+86-021-6989-5597
Address:No.80 Yichuan Rd., Putuo District,Shanghai,P.R.China
AllyChem Co., Ltd., Dalian, China（BBChem）
Contact:+86-411-62313318/62313328
Address:No.5 of Jinbin Road, Jinzhou New District, Dalian City, Liaoning Province, P.R.China
Beijing Cooperate Pharmaceutical Co.,Ltd
website:http://www.cooperate-pharm.com/
Contact:86-01060279497
Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Doi:10.1039/b905104j
(2009)Doi:10.1021/ja00190a053
(1989)Doi:10.1002/anie.200903903
(2009)Doi:10.1135/cccc2009001
(2009)Doi:10.1039/b905556h
(2009)Doi:10.1007/s11164-012-0575-0
(2013)
