
Chemistry of Heterocyclic Compounds p. 562 - 566 (1988)
Update date:2022-08-05
Topics:
Luk'yanenko, N. G.
Lobach, A. V.
Nazarova, N. Yu.
Karpenko, L. P.
Lyamtseva, L. N.
Chiral azacrown ethers were obtained by the condensation of (4S,5S)-4,5-ditosyloxymethyl-2,2-dimethyl-1,3-dioxolane with 6-benzyl-3,9-dioxa-6-azaundecane-1,11-diol.Their debenzylation and deacetalization were realized.The enantiomeric selectivity in the complex formation between the obtained crown ethers and the hydrochlorides of L- and D-valine methyl esters was determined by a potentiometric method.The chiral azacrown ethers exhibit higher enantioselectivity than their oxygen analogs.
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